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Meningococcal Quadrivalent Conjugate Vaccine


Vaccination is the best protection against meningococcal infections and their complications. For instance, meningitis that is an infection of the brain lining and meningococcemia that is an infection of the blood are 2 serious infections caused by meningococcus.

There are different serogroups or types of meningococcus, among other serogroups A, B, C, Y and W135. This vaccine protects against serogroups A, C, Y and W135.

The vaccine is recommended for persons with a high risk of infection from meningococcus. It is also recommended for persons travelling to regions where the risk of meningococcal infection is high.


Some symptoms may be caused by the vaccine, e.g. redness at the injection site. Other problems may occur by chance and are not related to the vaccine, e.g. cold, gastro, headache.

Meningococcal quadrivalent conjugate vaccine is safe. Most reactions are harmless and do not last long.

The Nature and Frequency of Possible Reactions to Vaccine

Frequency Possible reactions to the vaccine

In most cases
(more than 50% of people)

  • Pain at the injection site

Very often
(less than 50% of people)

  • Redness and swelling at the infection site
  • Headache, muscle pain, fatigue, discomfort, nausea, pain in joints, diarrhea, loss of appetite, irritability, drowsiness (sleepiness)


(less than 10% of people)

  • Fever, shivering, vomiting, skin rash

What to do After Vaccination

Tips to follow immediately following vaccination

Wait 15 minutes before leaving premises where vaccine is received. If an allergic reaction occurs, the symptoms will appear a few minutes after the vaccination.

If you feel side effects, immediately inform the person giving the vaccine. That person will be able to treat you immediately.

Tips to follow at home

If you experience redness, pain or swelling at the injection site, apply a cold, damp compress on it.

Use medication for fever or discomfort if needed.

When to Seek Medical Help

See a doctor if one of the following applies to you:

  • You experience serious and unusual symptoms
  • Your symptoms get worse instead of improving
  • Your symptoms last over 48 hours

Last update: June 25, 2015 10:50 AM

The information on this website by no means replaces the advice of a health professional. If you have questions regarding your health, contact Info-Santé 8-1-1 or see a health professional.

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